Table 2. Results of morphological scoring in hamsters.
Edema | Inflammation | Necrosis | Hemorrhage | Total | |
---|---|---|---|---|---|
Saline | 0.13 ± 0.35 | 0.00 ± 0.00 | 0.25 ± 0.46 | 0.00 ± 0.00 | 0.38 ± 0.52 |
Caerulein (low) | 1.19 ± 0.26* | 0.88 ± 0.64 | 0.38 ± 0.52 | 0.00 ± 0.00 | 2.44 ± 1.27 |
Caerulein (high) | 3.00 ± 0.53* | 1.56 ± 0.56* | 1.75 ± 0.71* | 0.00 ± 0.00 | 6.31 ± 1.31* |
L-arginine (low) | 2.56 ± 0.42* | 2.81 ± 0.88* | 3.13 ± 0.79* | 2.75 ± 1.83 | 11.25 ± 3.25* |
L-arginine (high) | 4.31 ± 0.65* | 4.00 ± 0.00* | 4.00 ± 0.00* | 4.00 ± 0.00* | 16.31 ± 0.65* |
Retrograde-saline | 0.94 ± 1.08 | 0.75 ± 0.53 | 0.50 ± 0.53 | 0.50 ± 0.93 | 2.69 ± 1.91 |
Retrograde-Na-taurocholate | 3.63 ± 0.52*# | 3.25 ± 0.80*# | 3.75 ± 0.53*# | 3.75 ± 0.71*# | 14.38 ± 1.43*# |
EtOH | 0.50 ± 0.32 | 0.5 ± 0.63 | 0.25 ± 0.27 | 0.00 ± 0.00 | 1.25 ± 0.88 |
POA | 0.17 ± 0.26 | 0.00 ± 0.00 | 0.17 ± 0.26 | 0.00 ± 0.00 | 0.33 ± 0.41 |
EtOH + POA (low) | 2.25 ± 0.69*§¶ | 2.25 ± 1.13*§¶ | 1.75 ± 0.82*§¶ | 0.33 ± 0.52 | 6.58 ± 2.29*§¶ |
EtOH + POA (high) | 2.42 ± 0.66*§¶ | 2.67 ± 1.33*§¶ | 1.58 ± 0.74*§¶ | 0.17 ± 0.41 | 6.83 ± 2.79*§¶ |
Values are mean ± SD of 8 mice, statistical analysis was performed using the Mann−Whitney test, *p < 0.05 compared to Saline group, #p < 0.05 compared to Retrograde-saline group, §p < 0.05 compared to ethanol (EtOH) group, ¶p < 0.05 compared to POA group.