Table 1.
Univariate analysis of demographic, clinical, and outcomes variables for stroke patients with and without splenic contraction.
| Patients without SC (n = 94) | Patients with SC (n = 64) | p value | OR (95% CI) | |
|---|---|---|---|---|
| Gender (Female), n (%) | 48 (51.1) | 29 (45.3) | 0.48 | 1.26 (0.66–2.38) |
| Race, n (%) | ||||
| • White | 70 (76.9) | 27 (44.3) | Referent category | |
| • African American | 21 (23.1) | 34 (55.7) | < 0.01 | 4.19 (2.08–8.47) |
| Ethnicity (Hispanic), n (%) | 19 (20.2) | 13 (20.3) | 0.99 | 1.01 (045–2.22) |
| Age (>75 years), n (%) | 26 (27.7) | 28 (43.8) | 0.04 | 2.03 (1.04–3.97) |
| Stroke type | ||||
| • Ischemic stroke | 69 (73.4) | 49 (76.6) | Referent category | |
| • ICH | 25 (26.6) | 15 (23.4) | 0.66 | 0.84 (0.40–1.77) |
| Stroke onset to first spleen scan (hours), median (IQR) | 5.3 (2.9–13.9) | 4.7 (3.3–12.2) | 0.49 | 0.99 (0.95–1.03) |
| Stroke onset to first spleen scan < 6 hours, n (%) | 49 (55.7) | 38 (60.3) | 0.57 | 1.21 (0.63–2.33) |
| NIHSS, median (IQR) | 7 (4–16) | 11 (7–18) | 0.03 | 4.00 (0.26–7.75)a |
| Serial NIHSS, median (IQR) | 7 (2–13.5) | 10 (4–19) | 0.01 | 3.00 (1.16–4.83)a |
| Hypertension, n (%) | 78 (82.9) | 54 (84.4) | 0.82 | 1.11 (0.46–2.63) |
| Chronic pulmonary disease, n (%) | 3 (3.2) | 5 (7.8) | 0.21 | 2.54 (0.58–11.04) |
| Diabetes mellitus, n (%) | 25 (26.6) | 17 (26.6) | 0.99 | 0.99 (0.48–2.05) |
| Malignancy, n (%) | 7 (7.5) | 3 (4.7) | 0.48 | 0.60 (0.15–2.43) |
| Coronary artery disease, n (%) | 9 (9.7) | 7 (10.9) | 0.79 | 1.15 (0.40–3.25) |
| Hypercholesterolemia, n (%) | 26 (27.9) | 14 (21.9) | 0.39 | 0.72 (0.34–1.52) |
| Smoking, n (%) | 21 (22.3) | 14 (21.9) | 0.95 | 0.97 (0.45–2.09) |
| Atrial fibrillation, n (%) | 14 (15.1) | 12 (18.8) | 0.54 | 1.30 (0.55–3.03) |
| Previous stroke, n (%) | 14 (15.1) | 21 (32.8) | 0.01 | 2.75 (1.27–5.96) |
| Chronic renal disease, n (%) | 4 (4.3) | 2 (3.1) | 0.71 | 0.72 (0.13–4.04) |
| Discharge mRS (median–IQR) | 3.5 (3–4) | 4 (3–5) | 0.17 | 0.5 (−0.41–2.42) |
| UTI or pneumonia, n (%) | 3 (3.2) | 5 (7.8) | 0.21 | 2.57 (0.59–11.16) |
| Mortalityb, n (%) | 6 (6.4) | 7 (10.9) | 0.31 | 1.80 (0.58–5.63) |
SC: splenic contraction. Defined as observed volume < expected 50th percentile for given gender and body surface area category by at least 20 cm3.
a
Difference in median and the 95% confidence interval of the difference. Null value for 95% confidence interval = 0.
b
In-patient mortality.