Table 2.

NMR and X-ray crystallography structures of aptamers for small molecules that have been deposited into the Protein Data Bank (PDB).

Target	PDB-ID	Chemistry	Technique	Year	References
AMP	1AM0	RNA	NMR	1996	Jiang et al., 1996
AMP	1RAW	RNA	NMR	1996	Dieckmann et al., 1996
AMP	1AW4	DNA	NMR	1997	Lin et al., 1997
Argininamide	1DB6	DNA	NMR	2000	Robertson et al., 2000
Arginine	1KOC	RNA	NMR	1996	Yang et al., 1996
Arginine	2ARG	DNA	NMR	1998	Lin et al., 1998
Biotin	1F27	RNA	X-ray	2000	Nix et al., 2000
Citrulline	1KOD	RNA	NMR	1996	Yang et al., 1996
Cyanocobalamin	1DDY	RNA	X-ray	2000	Sussman et al., 2000
Cyanocobalamin	1ET4	RNA	X-ray	2000	Sussman and Wilson, 2000
DFHBI	4Q9Q, 4Q9R, 4KZD, and 4KZE	RNA	X-ray	2014	Huang et al., 2014
DFHBI	4TS2 and 4TS0	RNA	X-ray	2014	Warner et al., 2014
FMN	1FMN	RNA	NMR	1996	Fan et al., 1996
GTP	2AU4	RNA	NMR	2006	Carothers et al., 2006
Malachite Green	1F1T	RNA	X-ray	2000	Baugh et al., 2000
Malachite Green	1Q8N	RNA	NMR	2004	Flinders et al., 2004
Neomycin B	1NEM	RNA	NMR	1999	Jiang et al., 1999
Streptomycin	1NTB and 1NTA	RNA	X-ray	2003	Tereshko et al., 2003
Tetracycline	3EGZ	RNA	X-ray	2008	Xiao et al., 2008
Theophylline	1EHT	RNA	NMR	1997	Zimmermann et al., 1997
Theophylline	1O15	RNA	NMR	2003	Clore and Kuszewski, 2003
Tobramycin	1TOB	RNA	NMR	1997	Jiang et al., 1997
Tobramycin	2TOB	RNA	NMR	1998	Jiang and Patel, 1998

AMP, adenosine monophosphate.