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. 2016 Jun 15;8:67. doi: 10.1186/s13073-016-0312-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — A model of gut microbial changes following RYGB. Blue boxes show inferred changes in microbial features (functional potential or taxonomic), while green boxes show the effects induced by RYGB either in the gut or in the host metabolism. Black boxes indicate hypotheses based on our data or other studies. Arrows connect shifts that are related. Since we did not measure inflammation markers we do not report an increase or decrease in inflammation, but we connect it to an observed change based on existing literature. All features shown here exhibited changes 3 months after RYGB and most maintained the changes up to 1 year after RYGB. Asterisks denote features that did not maintain the changes 1 year after RYGB