Table 1.

The top five biological networks identified by IPA

Top functions (Networks)	Associated molecules	Score	Focus molecule
Cellular movement, cell morphology, cellular function and maintenance	Catenin, BAG3, BCAR1, BCR, c-Src, CAV1, CRK, CTNND1, DOCK1, EPHA2, F Actin, FAK,GAB1, Igm, LASP1, MLLT4, MYO1E, NFkB, p85, PDLIM1, PEAK1, PI3K p85, PLC gamma, PLCG1, PPP1CA, PPP1CB, PTPN6, PTPN11, Ras, Rock, SHC1, SLC9A1, TJP1, TJP2, TNK2	37	23
Cellular movement, cancer, cellular development	ADAM9, ANXA2, Ap1, AXL, BCAR3, calpain, CDH1, COL17A1, CTTN, EGFR, EPS15, ERBB2, ERK1/2, FAM120A, G protein alphi, INPPL1, IQGAP1, ITGB4, JAK2, Mapk, Mek, Mmp, PIK3R1, PTK2, PTPRE, PTPRK, Rac, Rap1, RIN1, SCAMP3, SDCBP, Shc, SRC,Vegf	35	22
Cardiac arrythmia, cardiovascular disease, organismal injury and abnormalities	ARHGAP35, Cg, CLDN1, DSG2, DSP, ERK, ER, FLNB, FSH, FUBP3, Growth harmone, HDAC, HNRNPA1, HNRNPA2B1, HNRNPK, Hsp70, Hsp90, HSP90AA1, JNK, JUP, LDLR, LH, PCBP2, PCDH7, PKP2, PLIN3, Ras homologue, RASAL2, RNA polymerase II, Secretase gamma, SPTAN1, TNS3, TUBA1A, TUBA1C	33	21
Cellular assembly and organization, cellular function and maintenance, cell-to-cell signaling and interaction	ABLIM1, Akt, ANXA1, CCDC88A, CD3, CFL1, CRKL, ERRFI1, Fibrinogen, G protein beta gamma, Gsk3, Hsp27, IgG, LDL, MAP2K1/2, MAPK1, MAPK3, MAPK13, MAPK14, NEDD9, P38 MAPK, PAG1, PDGF BB, PI3 K (complex), PI3 K (family), pkc, PP2A, PRKCD, PTK2B, SHANK2, STAT5a/b, SYK, TCR, VAV2, YES1	26	18
Embryonic development, hair and skin development and function, organ development	AHNAK, AIM1, CASP14, COL7A1, CTNNB1, EPHA1, EPHB2, ERBB2, ERBB2IP, ETV5, FOXQ1, GCHFR, GRB2, HENMT1, HNRNPA3, KRT5, KRT7, KRT14, KRT16, KRT80, NRCAM, OCIAD2, PABPC4, PHLDB1, PKP3, PKP4, QPCT, RPS17, SCG5, SCGB2A2, SHB, SMARCA4, STAT5A, TSPAN13, ZNF185	17	13