Table 3.
Spontaneously reported PAH symptoms and impacts selected for inclusion in the draft PRO
| n (%) | |
|---|---|
| Symptoms (n = 25 patients) | |
| Shortness of breath | 23 (92 %) |
| Tiredness/fatigue/weakness/lack of energy | 21 (84 %) |
| Swelling in ankles or legs | 19 (76 %) |
| Rapid heartbeat/heart fluttering | 19 (76 %) |
| Chest pain/tightness | 16 (64 %) |
| Dizziness/lightheadedness | 14 (56 %) |
| Cough/dry cough | 13 (52 %) |
| Loss of appetite | 10 (40 %) |
| Swelling in stomach area | 6 (24 %) |
| Impacts (n = 5 focus groups)a | |
| Physical | |
| Stairs/exercise | 5 (100 %) |
| Carrying/lifting things | 4 (80 %) |
| Walking slower or with difficulty | 3 (60 %) |
| Activities of Daily Living | |
| Household chores | 5 (100 %) |
| Errands | 5 (100 %) |
| Work (effects on career or school/reducing hours) | 5 (100 %) |
| Washing/dressing | 3 (60 %) |
| Social Activities | |
| Needing help from others | 4 (80 %) |
| Going out to social activities | 3 (60 %) |
| Maintaining relationships | 3 (60 %) |
| Feeling embarrassed | 2 (40 %) |
| Cognition | |
| Concentration/memory/articulating thoughts/slow thinking | 3 (60 %) |
| Emotions | |
| Sad | 4 (80 %) |
| Frustrated/angry/mad | 4 (80 %) |
| Anxious/worried/stressed/loss of control | 3 (60 %) |
aRefers to difficulties in the listed areas