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. 2016 Jun 14;18:140. doi: 10.1186/s13075-016-1037-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Frequency of GCs in spleens from LNT-Igk-Ctrl and LNT-Igk-CII mice after CIA induction. Frequency of GCs per follicle in spleens a 15 days after immunization from LNT-Igk-Ctrl mice (n = 6) and LNT-Igk-CII mice (n = 6) or b 29 days after immunization from LNT-Igk-Ctrl mice (n = 3) and LNT-Igk-CII mice (n = 3). GC germinal centre