Table 2.

Clinical outcome of the immunized pigs following virulent challenge

Groups	Days to fever onset	Fever ratea	Fever frequencyb	Survival rate
A: rAdV-SFV-E2 (106 TCID50)	–	0/4	0/60	4/4
B: rAdV-SFV-E2 (105 TCID50) + BG (1010 CFU)	–	0/4	0/60	4/4
C: rAdV-SFV-E2 (105 TCID50)	3	3/4	14/50	3/4
D: BG (1010 CFU)	3	4/4	27/46	0/4
E: DMEM	3	4/4	27/44	0/4

Five groups of pigs (n = 4) were immunized and challenged as described in the “Materials and methods” section. Following challenge, the clinical signs and rectal temperatures were recorded daily. Fever is defined as rectal temperature ≥40.5 °C.

– no fever, CFU: colony forming units.

^aNumbers of pigs showing fever/total numbers of pigs in each group.

^bTotal days with any pig showing fever/total days of monitored for all the pigs in a group following virulent challenge.