Table S1.
Estimation of excess lifetime costs associated with peptic ulcer disease
| Calculation step | Equation/notation | Estimate |
|---|---|---|
| Excess LTCs associated with PUD due to continuing H. pylori infection, US$ | LTCPUD=(PPUD[w]−PPUD[wo])·CPUD | 28.09 |
| Expected cost per patient with PUD, US$ | CPUD=Cmed+Chosp | 249.65 |
| Expected cost per patient of PUD-related hospitalization, US$ | Chosp=PPUD[hosp]·CPUD[hosp] | 8.90 |
| Cost of GI hospitalization event due to PUD, US$ | CPUD[hosp] | 8,896.00 |
| Probability of GI hospitalization event due to PUD, % | PPUD[hosp] | 0.10 |
| Expected cost per patient of PUD regardless of hospitalization (managed by medication), US$ | Cmed=tPUD[med]·CPUD[med] | 240.75 |
| Duration of PUD, years | tPUD[med] | 0.50 |
| Cost/year of managing PUD with medication, US$ | CPUD[med] | 481.50 |
| Excess lifetime risk of PUD due to continuing H. pylori infection, % | PPUD[w]−PPUD[wo] | 11.25 |
| Lifetime risk of developing PUD with continuing H. pylori infection, % | PPUD[w] | 15.00 |
| Lifetime risk of developing PUD without continuing H. pylori infection, % | PPUD[wo] | 3.75 |