Table 2.
Drug Therapy
| No. (%) of Patients |
||
|---|---|---|
| Drug | Acute MI Cases (n=2316) |
Controls (n=9700) |
| Concomitant antidiabetic drugs | ||
| First-generation sulfonylurea | 11 (0.5) | 28 (0.3) |
| Nonsulfonylurea secretagog | 138 (6.0) | 560 (5.8) |
| α-Glucosidase inhibitor | 65 (2.8) | 223 (2.3) |
| Cardiovascular drugs | ||
| Cholesterol-lowering drug | 1329 (57.4) | 4902 (50.5) |
| Diuretic | 1301 (56.2) | 5183 (53.4) |
| β-Blocker | 1060 (45.8) | 3519 (36.3) |
| ACE inhibitor or ARB | 1717 (74.1) | 6771 (69.8) |
| Calcium channel blocker | 1029 (44.4) | 3950 (40.7) |
| Nitrate | 979 (42.3) | 2850 (29.4) |
| α-Blocker | 131 (5.7) | 567 (5.9) |
| Antiplatelet drug | 1202 (51.9) | 4393 (45.3) |
| Digoxin | 395 (17.1) | 1400 (14.4) |
| Antiarrhythmic | 20 (0.9) | 130 (1.3) |
| Psychotropic drugs | ||
| Benzodiazepine | 493 (21.3) | 2251 (23.2) |
| Nonbenzodiazepine hypnotic |
340 (14.7) | 1510 (15.6) |
| Anticonvulsant | 376 (16.2) | 1919 (19.8) |
| Opiate | 1028 (44.4) | 4610 (47.5) |
| Atypical antipsychotic | 216 (9.3) | 1368 (14.1) |
| Antidepressant | 866 (37.4) | 4045 (41.7) |
| Other drugs | ||
| Antibiotic | 1629 (70.3) | 7022 (72.4) |
| Corticosteroid | 290 (12.5) | 1450 (15.0) |
| Selective estrogen receptor modulatora |
48 (2.1) | 250 (2.6) |
| Hormone replacementa | 184 (7.9) | 1007 (10.4) |
MI = myocardial infarction; ACE = angiotensin-converting enzyme; ARB = angiotensin II receptor blocker.
a
Estimated among men and women.