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. 2016 Jun 15;3:16013. doi: 10.1038/mto.2016.13

Figure 2.

Figure 2

Tumor-initiating cells (TICs) are highly tumorigenic when compared to equal number of parent cells injected. (a) Tumors initiated with 1E5 cells of each tumor population were examined histologically. In addition to growing much faster, TIC tumors (c) exhibited much higher levels of histologic atypia compared to tumors initiated by parent cells (b) as noted by H&E staining.