| Right Ventricular pump |
290 |
| Left Vent pump |
850 |
|
Resistances
|
Hg.s ml
-1. ml
-1
|
| Aortic R |
0.04 |
| Pulmonary Artery R |
0.06 |
| Muscle R |
0.06 |
| Renal A R |
0.1 |
| SM A R |
1 |
| Hep A R |
0.2 |
| Vena cava R |
0.001 |
| Somatic Vein R |
0.01 |
| Renal V R |
0.01 |
| Portal V R |
0.005 |
| Hep V R |
0.001 |
| Hep shunt R |
0.4 |
|
Distensibility
|
mm Hg
-1
|
| Left Vent compliance |
1E-4 |
| Somatic vein compliance |
0.01 |
| Aortic compliance |
0.001 |
| SM cap compliance |
0.005 |
| Hep sin compliance |
0.005 |
| Splenic & Coeliac compliance |
0.05 |
| Renal compliance |
0.05 |
| Sys compliance |
0.1 |
| H sinusoid compliance |
0.005 |
|
Glucose parameters.
|
|
| Intestinal glucose pump V |
5 mmole s
-1
|
| Paracellular P
gl
|
0.15 μm s
-1
|
| GLUT2 V
max
|
3 mmole s
-1
|
| Renal Glucose T
m
|
1.2 mmole s
-1
|
| GLUT1 K
m
|
1.3 mM |
| GLUT2 K
m
|
20 mM |
| Somatic glucose metabolic coef. |
0.5 mmole s
-1
|
| Somatic insulin-dependent metabolic coef. |
8.5 mmole s
-1
|
| Non-insulin-dependent metabolic coef. |
0.65 mmole s
-1
|
| B cell K
m (glucose)
|
17 mM |
|
Insulin parameters
|
|
| K
m insulin
|
200 pM |
| Insulin loss rate (Hepatic) |
1.4 s
-1
|
| Insulin sensitivity coef. |
0.5 |
| insulin loss rate (Somatic) |
0.1 s
-1
|
|
Glucagon parameters
|
|
| Glucagon coef. Hepatic |
150 |
| Glucagon loss rate (Hepatic) |
0.5 s
-1
|
| Glucagon coeff. (somatic) |
150 |
| Glucagon loss rate (somatic) |
0.5 s
-1
|
| K
m glucagon
|
2 nM |
|
GLP-1parameters
|
|
| K
GLP-1
|
1 nM |
| GLP-1 loss rate (somatic) |
0.22 s
-1
|
| GLP-1 hepatic) sensitivity coef. |
2 |
| V
m GLP-1 |
20 nmole s
-1
|
| GLP-1(somatic) sensitivity coef. |
2 |
