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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: J Intensive Care Med. 2014 Apr 14;31(3):187–192. doi: 10.1177/0885066614530659

Table 2.

Association Between Magnesium Concentration and Mild Lactic Acidosis.

Odds Ratio for Lactic Acidosis (Lactate > 2 mmol/L)
Mg < 1.6 1.6 ≤ Mg < 1.8 1.8 ≤ Mg < 2.1 Mg ≥ 2.1 Per 1 mg/dL Increase in Mg
Model #1a 1.85 (1.64–2.08) <.001 1.28 (1.13–1.45) <.001 Reference 1.14 (1.02–1.27) .02 0.75 (0.69–0.83) <.001
Model #2b 1.72 (1.53–1.95) <0.001 1.29 (1.13–1.46) <.001 Reference 1.07 (0.96–1.20) .21 0.74 (0.67–0.82) <.001
Model #3c 1.71 (1.51–1.94) <0.001 1.29 (1.13–1.47) <.001 Reference 1.09 (0.97–1.23) .16 0.75 (0.67–0.83) <.001

Abbreviations: ICU, intensive care unit; SAPS, Simplified Acute Physiology Score; SBP, systolic blood pressure.

a

Includes unadjusted magnesium.

b

Adjusts for age, gender, ethnicity, and SAPS.

c

Adjusts for age, gender, ethnicity, SAPS score, comorbidities, ICU type, admission serum creatinine, SBP, and oliguria during first 24 hours of ICU care.