. Author manuscript; available in PMC: 2016 Jun 15.

Published in final edited form as: J Intensive Care Med. 2014 Apr 14;31(3):187–192. doi: 10.1177/0885066614530659

Table 4.

Adjusted Association of Magnesium Concentration and Mild Lactic Acidosis in Those at Risk of Magnesium Deficiency.^a

Odds Ratio for Lactic Acidosis (Lactate > 2 mmol/L)

	Mg < 1.6	1.6 ≤ Mg < 1.8	1.8 ≤ Mg < 2.1	Mg ≥ 2.1	Per 1 mg/dL Increase in Mg
Diabetics	n = 356	n = 349	n = 588	n = 729	0.63 (0.5–0.79) <.001
	2.02 (1.51–2.72) <.001	1.37 (1.03–1.82) .03	Reference	0.96 (0.76–1.21) .71
Alcoholics	n = 179	n = 126	n = 166	n = 155	0.65 (0.42–0.99) .05
	1.92 (1.16–3.19) .01	1.54 (0.90–2.64) .12	Reference	1.25 (0.74–2.10) .40
Nondiabetic, nonalcoholic	n = 1501	n = 1153	n = 1776	n = 1912	0.79 (0.70–0.89) <.001
	1.63 (1.41–1.90) <.001	1.25 (1.07–1.46) .01	Reference	1.12 (0.99–1.29) .11

Abbreviations: ICU, intensive care unit; SAPS, Simplified Acute Physiology Score; SBP, systolic blood pressure.

Adjusts for age, gender, ethnicity, SAPS score, comorbidities, ICU type, admission serum creatinine, SBP, and oliguria during first 24 hours of ICU care.