Table 1. Baseline characteristics.
Sham (n = 6) | SI + CC90 (n = 8) | SI + CC120 (n = 8) | p-value | |
---|---|---|---|---|
Age (days) | 2.0 (1.0–2.0) | 2.0 (1.5–3.5) | 2.0 (1.5–2.5) | 0.62 |
Weight (kg) | 2.0 (1.7–2.2) | 2.0 (1.9–2.2) | 2.0 (1.9–2.0) | 0.84 |
Heart rate (bpm) | 202 (187–222) | 238 (223–249) | 221 (205–246) | 0.07 |
MAP (mmHg) | 81 (69–89) | 74 (64–91) | 79 (72–89) | 0.81 |
CO (mL/kg/min) | 231 (198–306) | 334 (308–378) | 201 (172–251) | 0.18 |
Ejection Fraction (%) | 27 (27–30) | 27 (23–40) | 21 (14–27) | 0.08 |
Max dp/dt (mmHg) | 3984 (3308–6031) | 6719 (5187–8045) | 5265 (3665–6325) | 0.09 |
Tau (ms) | 19 (18–21) | 14 (13–16) | 15 (13–19) | 0.48 |
Carotid flow (mL/min/kg) | 30 (27–33) | 41 (33–47) | 37 (32–43) | 0.16 |
Cerebral oxygenation (%) | 38 (34–40) | 44 (43–51) | 43 (39–46) | 0.15 |
pH | 7.4 (7.4–7.4) | 7.4 (7.3–7.4) | 7.4 (7.3–7.4) | 0.73 |
Base excess (mmol/L) | -2 (-2~1) | -4 (-7~-2) | -1(-6~2) | 0.32 |
paCO2 (torr) | 41 (39–46) | 39 (35–43) | 41 (36–42) | 0.89 |
SpO2 (%) | 91 (90–92) | 92 (88–93) | 92 (90–93) | 0.82 |
Lactate (mmol/L) | 3.2 (3.0–4.23) | 3.8 (3.5–4.6) | 3.1 (2.5–4.4) | 0.47 |
Arterial hemoglobin (g/L) | 78 (64–84) | 76 (71–82) | 77 (70–84) | 0.82 |
Data are presented as median (IQR); MAP- Mean arterial blood pressure, CO—Cardiac output