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. 2016 Jun 15;11(6):e0157538. doi: 10.1371/journal.pone.0157538

Fig 3. 4-PBA reverses and prevents pulmonary arterial and right ventricular remodeling in a rat model of MCT-induced PAH.

Fig 3

The percent medial wall thickness (MWT%, A), the ratio of vascular wall area (WA) / total vascular area (WA%, B), the ratio of vascular lumenal area (VA) / total vascular area (luminal erea, LA%, C) and the right ventricular hypertrophy index (RVHI%, D) were examined in the NORMAL, PAH, REV and PRE groups (n = 10 for each group). Compared to the PAH group, significantly lower MWT%, WA% and RVHI% values were observed in the other groups (A, B and D), while significantly higher LA% values were observed (C). ***p < 0.001.