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. 2016 Jun 15;11(6):e0156942. doi: 10.1371/journal.pone.0156942

Table 2. Output features of the algorithm.

Feature Description
Spheroid center The coordinates of the 3D ellipsoid center of the spheroid
Ellipsoid axes The axes and their dimensions of the fitted ellipsoid
Spheroid mean intensity The mean intensity of the 2D spheroid mask
# spots per spheroid The number of positive cells detected in a spheroid
Spot center The coordinates of the center of a detected positive cell
Spot intensity The intensity in the original image of the spot
Circularity A Podzceck-shape factor determining the resemblance of the spheroid contour to a circle
Roundness class of the spheroid Elliptical or non-elliptical
Attenuation class of the spheroid Full, half, or not analyzable spheroid
Spheroid area Area of the 2D spheroid mask
Spheroid volume Volume of the 3D ellipsoid