Fig. 3.

Significant structural change in OSA patients Pre and Post CPAP treatment.

The first row (Pre-) shows neuroanatomical structures that were noted as hypotrophic in OSA patients (N = 55) before any intervention, by comparison to matched healthy volunteers (N = 35); bilateral globus pallidi, left hippocampi and mid posterior section of corpus callosum. The second row (Post-) depicts hypertrophic changes noted in bilateral thalami following one month of treatment with CPAP; the longitudinal structural changes were calculated by normalization to the individual baseline volumes (refer to the equation).