FIGURE 4. Abundant taxa in the placental membrane microbiome are unaltered by treatment or mode of delivery.
Differences in bacterial taxa at the species level were determined by Manhattan distance and visualized using a heat map. Subjects clustered by virtue of gestational age (term [orange] vs preterm [green]) and by histologic chorioamnionitis (yes: dark blue, no: dark red, mild: gray). Significance based on antibiotic treatment (yes: blue, no: red, unknown: gray), use of betamethasone (yes: green, no: pink, unknown: gray), or mode of delivery (vaginal: brown, cesarean delivery: light blue) was not detected.
Prince et al. Placental microbiota and their metabolic pathways in PTB and chorioamnionitis. Am J Obstet Gynecol 2016.