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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Am J Obstet Gynecol. 2016 Mar 7;214(5):627.e1–627.e16. doi: 10.1016/j.ajog.2016.01.193

FIGURE 6. Bacterial metabolic pathways are altered in association with histologic chorioamnionitis.

FIGURE 6

Because of differences in bacterial taxa, cohorts were analyzed by gestational age (term and pre-term). Alterations in inferred bacterial metabolic pathways were analyzed using Wilcoxon rank sum test. A, Term subjects without chorioamnionitis (red) were compared with term subjects with chorioamnionitis (blue). Butanoate metabolism (top) and riboflavin metabolism (bottom) is significantly decreased in term subjects without chorioamnionitis (P = .024 and P = .003, respectively). B, Preterm subjects without chorioamnionitis (red) were compared with preterm subjects with chorioamnionitis (blue). The pentose phosphate pathway and glycerophospholipid metabolism are significantly increased (P = .003 and P = .022, respectively).

Prince et al. Placental microbiota and their metabolic pathways in PTB and chorioamnionitis. Am J Obstet Gynecol 2016.