. 2016 Apr 13;7:212–220. doi: 10.1016/j.ebiom.2016.04.005

Table 1.

NIH criteria for NF1.

NIH diagnostic criteria for Neurofibromatosis type 1
Two or more of the following: 6 or more café au lait macules (0.5 cm in children or 1.5 cm in adults) 2 or more cutaneous/subcutaneous neurofibromas or one plexiform neurofibroma Skin fold freckling Optic pathway glioma 2 of more Lisch nodules (iris hamartomas seen on slit lamp examination) Bony dysplasia (sphenoid wing dysplasia, bowing of long bone, pseudarthrosis) First degree relative with NF1

NIH diagnostic criteria for Neurofibromatosis type 1

Two or more of the following:
6 or more café au lait macules (0.5 cm in children or 1.5 cm in adults)
2 or more cutaneous/subcutaneous neurofibromas or one plexiform neurofibroma
Skin fold freckling
Optic pathway glioma
2 of more Lisch nodules (iris hamartomas seen on slit lamp examination)
Bony dysplasia (sphenoid wing dysplasia, bowing of long bone, pseudarthrosis)
First degree relative with NF1