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Urinary Etio-S is associated with IC/BPS subjects. (a) ROC curve analysis on the discovery set of 40 healthy participants and 40 IC/BPS participants' Etio-S levels and GUPI scores. The area under the curve (AUC) value of 0.87 is statistically significant from the null hypothesis (p < 0.001). (b) ROC curve analysis on validation samples using urine Etio-S levels and GUPI scores. These results were confirmed in three independent experiments.
