Figure 3.
Cladogram displaying the multiple sequence alignment obtained with murine DEAD-box RNA helicase family members using Clustal Omega (http://www.ebi.ac.uk/clustalw/). Alignments were performed with sequences spanning and immediately flanking conserved motifs V and VI only. For example, this would correspond to 328-TTDLLARGIDVQQVSLVIN—-HRIGRGGRFGRKGVAINM-375 for eIF4AI. A complete list of sequences compared can be found in Figure S2 of Ref.78 The Entrez Protein IDs are in parenthesis. eIF4AI and eIF4AII are highlighted in yellow for easy reference.