Table 3.

Regional Gray Matter Volumetric Differences between Fallers and Non-Fallers

Regions		Non-fallers (N=36)		Fallers (N=30)
		Structural Volume (mm^3)	SD	Structural Volume (mm^3)	SD	p-value*
Frontal Areas	Laterality
Rostral anterior cingulate	RH	1882.83	302.69	2010.67	432.02	0.06
Caudal anterior cingulate	LH	1689.11	386.91	1763.20	524.04	0.22
Rostral middle frontal	LH	13073.47	1604.18	12827.17	1466.79	0.82
Caudal middle frontal	RH	5148.64	1036.34	5164.20	1075.81	0.47
Medial orbitofrontal	LH	4666.78	532.87	4430.53	583.39	0.22
Lateral orbitofrontal	LH	6608.39	904.32	6223.83	597.05	0.03
Pars opercularis	RH	3356.50	511.58	3368.80	491.18	0.53
Pars triangularis	LH	3070.56	405.37	2865.33	451.02	0.12
Pars triangularis	RH	3543.22	472.68	3335.60	400.60	0.14
Other Areas
Insula	LH	6215.03	628.92	5905.23	541.48	0.05
Insula	RH	6363.06	733.20	5881.10	641.23	0.01
Subcortical Areas
Total Amygdala		3010.43	419.57	2849.39	348.07	0.14
Amygdala	LH	1476.74	212.52	1391.48	220.38	0.11
Amygdala	RH	1533.69	248.16	1457.91	162.17	0.30
Total Pallidum		2801.71	351.94	2523.99	352.38	0.01
Pallidum	LH	1435.56	204.89	1264.29	204.10	0.01
Pallidum	RH	1366.15	194.06	1259.70	211.19	0.04
Total Hippocampus		7666.96	873.03	7191.10	712.6	0.02
Hippocampus	LH	3775.46	446.57	3551.86	363.28	0.04
Hippocampus	RH	3891.50	460.03	3639.23	402.26	0.03

Statistical comparisons were conducted by performing ANCOVA on SPSS.

Note: LH = Left-hemisphere; RH= Right-hemisphere.

^*All comparisons were adjusted for baseline age, total white matter hypointensity volume and estimated total intracranial volume. Bolded values represent p<0.05 and italicized values represent trend-level effects (p<0.10).