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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Aug 4;31(9):2070–2079. doi: 10.1161/ATVBAHA.111.227116

Figure 1.

Figure 1

Human neutrophil peptides (HNPs) induce leukocyte-monocyte interaction. A, Human monocyte adhesion on human coronary artery endothelial cells (HCAECs) after stimulation with HNPs for 4 hours. V indicates vehicle. B, Monocyte (defined by CD33 as surface marker) transmigration through HCAECs after stimulation with HNPs. C, Expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in HCAECs after stimulation with HNPs for 4 hours. D, CD11 expression 1 hour after HNP stimulation in primary human monocytes. E, Interleukin-8 (IL-8) production in coculture supernatants of HCAECs and monocytes stimulated with HNPs for 4 hours (n=5 experiments). F, Monocyte chemotactic protein-1 (MCP-1) production in HCAECs stimulated with HNPs for 4 hours (n=5 experiments). *P<0.05 vs V under identical conditions.