Table 3.
Outcome Measure Scores for Methamphetamine (MA)-, or Placebo (PBO)-paired Stimuli Across Four Test Sessions, Before (session 1) and After (sessions 6–8) Conditioning
| Session 1
|
Session 6
|
Session 7
|
Session 8
|
Sig. | |
|---|---|---|---|---|---|
| Mean(SEM) | Mean(SEM) | Mean(SEM) | Mean(SEM) | ||
| Outcome Measure | |||||
| Behavioral Preference (N=19) | 0.32(1.40) | 2.84(1.49) | 1.74(1.81) | 1.37(1.95) | S1vs6* |
| Attention (N=19) | |||||
| Initial MA first-gaze | 0.50(0.03) | 0.55(0.02) | 0.52(0.02) | 0.51(0.01) | S1vs6* |
| MA gaze time, in ms | 607.84(49.73) | 603.17(61.25) | 600.24(47.32) | 618.66(67.46) | |
| PBO gaze time, in ms | 521.93(61.30) | 558.46(61.92) | 615.25(70.35) | 634.05(80.17) | |
| Subjective Rating (N=19) | |||||
| MA Cue [median] | 86.80(2.7) [89.50] | 76.78(3.21) [75.50] | 72.64(4.06) [69.75] | 73.22(4.07) [75.25] | S1vs6*** S1vs7*** S1vs8*** |
| PBO Cue [median] | 85.08(3.27) [87.50] | 70.24(4.05) [72.75] | 69.87(4.36) [71.50] | 70.01(3.72) [69.50] | S1vs6*** S1vs7*** S1vs8*** |
Behavioral preference is given by MA-cue choices minus PBO-cue choices in forced choice task. Initial MA first-gaze is given as a proportion of first gazes towards the MA image divided by total number of valid gazes. MA and PBO gaze time are listed as average gaze time per stimulus. Subjective ratings scores are from a 100mm VAS. For subjective rating scores, non-normal distributions necessitated the use of non-parametric tests, which compared median values across sessions. Note:
p ≤ 0.016 and
p ≤ 0.001.