Table 2.

Details of the structures depicted in Figure 5.

Protein Name	Organism	PDB Code	Protein Classification	Resolution	Space Group	Unit cell	Rwork, Rfree	Year	Reference
photosystem I	Thermosynechococcus elongatus	3PCQ	membrane	8.98 Å	P63	281.0, 281.0, 165.2 90, 90, 120	0.25, 0.23	20101	(Chapman et al., 2011)
FABP3	Homo sapiens	3WXQ	soluble	1.6 Å	P212121	133.25, 226.26, 307.09 90, 90, 90	0.178, 0.222	20142	(Sugahara et al., 2015)
purple bacterial reaction center	Blastochloris viridis	4CAS	membrane	3.5 Å	P212121	104.8, 104.8, 104.8 90, 90, 90	0.295, 0.329	20131	(Johansson et al., 2013)
lysozyme	Gallus gallus	4ET8	soluble	1.9 Å	P43212	33.71, 54.85, 70,66 90, 90, 90	0.196, 0.229	20121	(Boutet et al., 2012)
cathepsin B	Trypanosoma brucei	4HWY	soluble	2.1 Å	P42212	57.90, 84.80, 384.30 90, 90, 90	0.182, 0.213	20121	(Redecke et al., 2013)
serotonin receptor 5-HT2B	Homo sapiens	4NC3	membrane	2.8 Å	C2221	79.0, 79.0, 38.0 90, 90, 90	0.227, 0.270	20131	(Liu et al., 2013)
photosystem II	Thermosynechococcus elongatus	4PBU	membrane	5.0 Å	P212121	125.40, 125.40, 54.56 90, 90, 90	0.262, 0.261	20141	(Kupitz et al., 2014)
δ-opioid receptor	Homo sapiens	4RWD	membrane	2.7 Å	C121	61.50, 122.20, 168.50 90, 90, 90	0.208, 0.238	20141	(Fenalti et al., 2015)
smoothened receptor	Homo sapiens	4O9R	membrane	3.2 Å	P1211	40.50, 157.30, 52.40 90, 97, 90	0.232, 0.278	20141	(Weierstall et al., 2014)
Cry3A	Bacillus thuringiensis	4QX0	soluble	2.8 Å	C2221	116.88, 134.81, 105.15 90, 90, 90	0.165, 0.192	20141	(Sawaya et al., 2014)
CPV17 polyhedrin	Uranotaenia sapphirina cypovirus	4S1K	soluble	2.2 Å	I23	156.23, 89.29, 96.42 90, 92.30, 90	0.14, 0.19	20151	(Ginn et al., 2015)
diacylglycerol kinase	Escherichia coli	4UYO	membrane	2.18 Å	P212121	75.30, 91.80, 141.70 90, 90, 90	0.208, 0.236	20141	(Li et al., 2015)
xylose isomerase	Streptomyces rubiginosus	4W4Q	soluble	2.0 Å	I222	94.00, 100.00, 103.00 90, 90, 90	0.159, 0.196	20142	(Sugahara et al., 2015)
photoactive yellow protein	Halorhodospira halophila	4WL9	soluble	1.6 Å	P63	66.90, 66.90, 40.80 90, 90, 90	0.198, 0.231	20141	(Tenboer et al., 2014)
SR Ca2+-ATPase	Oryctolagus cuniculus	4XOU	membrane	2.8 Å	C121	162.00, 76.30, 151.10 90, 109, 90	0.304, 0.343	20151	(Bublitz et al., 2015)
angiotensin II receptor	Homo sapiens	4YAY	membrane	2.9 Å	C121	72.80, 41.00, 167.70 90, 99.40, 90	0.228, 0.274	20151	(Zhang et al., 2015)
phycocyanin	Thermosynechococcus elongatus	4Z8K	soluble	2.5 Å	P63	153.40, 153.40, 39.64 90, 90, 120	0.187, 0.255	20151	(Conrad et al., 2015)
luciferin regenerating enzyme	Photinus pyralis	5D9B	soluble	1.5 Å	P212121	186.38, 186.38, 60.34 90, 90, 120	0.184, 0.232	20152	(Yamashita et al., 2015)
C-phycocyanin	Thermosynechococcus elongatus	4ZIZ	soluble	1.75 Å	H32	109.24, 109.24, 452.64 90, 90, 90	0.204, 0.254	20151	(Fromme et al., 2015)
rhodopsin-arrestin complex	Homo sapiens	4ZWJ	membrane, soluble	3.3 Å	P212121	48.21, 77.59, 84.76 90, 90, 90	0.252, 0.293	20151	(Kang et al., 2015)

¹denotes experiments done at LCLS

²denotes experiments done at SACLA.