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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Int J Parasitol. 2016 Apr 9;46(7):417–424. doi: 10.1016/j.ijpara.2016.03.006

Fig. 2.

Fig. 2

Enzymatic activity of recombinant Schistosoma mansoni SmSULT-OR sulfotransferase expressed from different allelic variants. This in vitro oxamniquine OXA activation assay quantifies DNA-OXA complexes by scintillation (counts per min) (see section 2.9). Bars show the mean of three replicates, while error bars are S.E.M. Enzyme carrying loss-of-function mutations, such as p.C35 or p.E142del, showed no OXA activation, while two newly identified alleles (p.G206V and p.N215Y) did not impair OXA activation. * P < 0.05.