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. Author manuscript; available in PMC: 2017 Jul 15.
Published in final edited form as: Biol Psychiatry. 2015 Dec 15;80(2):160–169. doi: 10.1016/j.biopsych.2015.12.008

Figure 4.

Figure 4

NT213739 genotype robustly predicts Oxtr expression. (a) NAcc OXTR density was associated with NT213739 genotype across three independent samples (Sample 1, adjusted R2=0.81; Sample 2, adjusted R2=0.90; Sample 3, adjusted R2=0.74). OXTR density in the insula (Ins) was not associated with NT213739. (b) (c) NAcc Oxtr mRNA density was significantly associated with NT213739 genotype (N=31, adjusted R2=0.69). (c) NAcc Oxtr mRNA density is significantly correlated with OXTR protein binding density (N=31). (d) Representative images highlighting the differences between NT213739 genotypes in Oxtr expression within the striatum, particulary the nucleus accumbens (NAcc). Black scale bar represents 100 µm.* P < 1×10−8. Data is shown as individual OXTR density (dpm/mg) or individual mRNA density (ROD) with trend line for the linear regressions.