Figure 5.
Relaxation responses of 11(S),12(R)-hepoxilin A3 (A), 11(R),12(S)-hepoxilin A3 (B), and hepoxilin A3-ether (C) in mouse mesenteric arteries constricted with either U46619 (●) or phenylephrine (○). Relaxation responses of 11(S),12(R)-hepoxilin A3 (D), 11(R),12(S)-hepoxilin A3 (E), and hepoxilin A3-ether (F) in mouse mesenteric arteries constricted with U46619 with (△) or without (▲) the sEH inhibitor, AUDA (1 μM). Each value represents the mean ± SEM. n = 7–15, * p < 0.05 compared to control.
