Table 3.
Correlations between intrinsic amygdala connectivity and early developmental social impairment
| seed region | +/− | R/L | region | voxels | p value | z-max | MNI (mm) | ||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | |||||||
| L LB | - | L | supracalcarine cortex (cingulate gyrus, posterior division, inferior frontal gyrus, pars opercularis, intracalcarine cortex, lateral occipital cortex, inferior division, lateral occipital cortex, superior division, lingual gyrus, occipital fusiform gyrus, occipital pole, precuneous cortex, superior parietal lobule, parietal operculum, angular gyrus, central opercular cortex, frontal pole, heschl’s gyrus, inferior frontal gyrus, pars triangularis, middle frontal gyrus, middle temporal gyrus, temporooccipital part, planum temporale, superior temporal gyrus, posterior division, supramarginal gyrus, anterior division, supramarginal gyrus, posterior division, vermis VI, VI, Crus I) | 13462 | .0000 | 4.34 | −4 | −88 | −10 |
| L LB | - | R | frontal pole (superior frontal gyrus, paracingulate gyrus, juxtapositional lobule cortex, cingulate gyrus, anterior division, inferior frontal gyrus, pars triangularis) | 2903 | .0000 | 3.99 | 4 | 58 | 38 |
| L LB | - | L | superior temporal gyrus, posterior division (supramarginal gyrus, anterior division, supramarginal gyrus, posterior division, planum temporale, middle temporal gyrus, posterior division, middle temporal gyrus, temporooccipital part, inferior temporal gyrus, temporooccipital part, heschl’s gyrus, angular gyrus, central opercular cortex) | 2011 | .0000 | 4.16 | −64 | −42 | 14 |
| L LB | - | L | inferior frontal gyrus, pars opercularis (middle frontal gyrus, precentral gyrus, postcentral gyrus) | 998 | .0000 | 3.88 | −58 | 14 | 16 |
Note. R = right, L = left. LB = laterobasal. Regions are labeled using the Harvard-Oxford Cortical Structural Atlas, the Harvard-Oxford Subcortical Structural Atlas, and the Probabilistic Cerebellar Atlas according to the peak p value within a contiguous cluster. Regions listed in parentheses were additional regions within the significant cluster. P-values are based on a whole-brain cluster correction for multiple comparisons.