. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: J Vasc Surg. 2015 Dec 15;64(2):484–493. doi: 10.1016/j.jvs.2015.01.031

Table I.

Data summary of the effect of neutrophil depletion on hind limb skeletal muscle after IR. Tissues from mice treated with anti-Neutrophil serum (ND) or normal serum (NS) were harvested 24 hours following IR. Neutrophil depletion significantly decreased plasma levels of circulating granulocytes (*) together with reduced MPO (†) and ETs (‡) in the injured tissue. However, Neutrophil depletion did not significantly alter hind limb perfusion, muscle fiber injury, the steady state level of ATP or γ-Actin protein levels. *,†, ‡ indicates significant difference from the normal serum group.

	Neutrophil Depleted (ND)	Normal Serum (NS)	P value
Granulocytes 10³/μl	0.14±0.02	1.11±0.15	*0.00004
MPO ng/mg	63.5±15.8	261.6±14.7	^†0.0001
ETs (MFI)	11.6±0.5	15±1.7	^‡0.041
Perfusion Ratio	1.128±0.232	0.848±0.097	0.46
% Injured Fibers	30.76±1.97	29.68±1	0.8
ATP nmole/μg protein	0.42±0.22	0.74±0.3	0.48
γ-Actin protein levels (AU)	2.5±0.54	3.56±0.78	0.25