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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 24;1019:156–163. doi: 10.1016/j.jchromb.2015.12.010

Figure 1.

Figure 1

Glyceryl Trinitrate (GTN) is denitrified by xanthine oxidase (XO) in endothelial cells to produce 1,2-glyceryl dinitrate (1,2-GDN) and NO2, which is reduced into NO and subsequently non-enzymatically oxidized to NO2 and NO3.