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. 2016 Jun 16;5(1):732. doi: 10.1186/s40064-016-2351-x

Table 4.

Comparative analysis of toxicity: original drug versus generic no. 2

Original drug
(n = 38)
Generic no. 2
(n = 17)
p
Hypersensitivity 1 (2.6 %) 0 (0 %) 1
Peripheral sensory neuropathy 2 (5.3 %) 2 (11.8 %) 0.58
Hematological toxicities 5 (13.2 %) 4 (23.5 %) 0.43
Febrile neutropenia 1 (2.6 %) 1 (5.9 %) 0.52
Gastrointestinal toxicity 2 (5.3 %) 3 (17.6 %) 0.16
Skin toxicity 0 (0 %) 3 (17.6 %) 0.026
Hand foot syndrome grade III 0 (0 %) 2 (11.8 %) 0.09
Ichthyosis-like eruption 0 (0 %) 1 (5.9 %) 0.3
Treatment discontinuation 3 (7.9 %) 5 (29.4 %) 0.09

Italic value indicates statistical significants