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Growth curves for PC3 (A), LNCaP (B), and MCF7 (C) WT and autophagy-deficient xenografts (10-12 tumors in 6 mice per group, experiments were repeated twice). (D) qPCR was used to confirm knockdown status of tumors generated from autophagy-deficient cells of the indicated genotypes (WT represents wild type; DK represents double knockdown). Data represent mean ± SEM, n = 3.
