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. 2016 Jun 9;18(6):387–397. doi: 10.1016/j.neo.2016.04.006

Figure 1.

Figure 1

Cell size changes measured by flow cytometry and light microscopy and cell cycle analysis. (A) Box-and-whisker plots of the FSC-W for OVCAR-8 and NCI/ADR-RES treated with various concentrations of Nab-paclitaxel (0, 100, and 500 nM). The sample size of each cohort is 6100. (B) Box-and-whisker plots of the cell size measured by light microscopy for OVCAR-8 and NCI/ADR-RES treated with various concentrations of Nab-paclitaxel (0, 100, and 500 nM). The sample size of each cohort is 620. For all the box-and-whisker plots, the 25th to 75th percentiles are blocked by the boxp; the black and red bands inside the box are the median and mean, respectively; and the whiskers mark the SD. ****P < .0001 as measured by one-way ANOVA with an FDR posttest. (C) Histograms of the emission light intensity of PI-labeled NCI/ADR-RES and OVCAR-8 cells treated with Nab-paclitaxel at 0 (black line), 100 (blue line), and 500 nM (red line).