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. 2016 Jun 16;10:160. doi: 10.3389/fncel.2016.00160

Table 1.

Embryo demographics at thawing, timing of different developmental stages after thawing, the number of embryos that developed into blastocysts, and the number of high-quality embryos following treatment with 0.25 or 0.5 μM fluoxetine.

Embryo demographics and time difference from thawing (hours) Control na = 16 median (IQR) 0.25 μM fluoxetine na = 16 median (IQR) 0.5 μM fluoxetine na = 16 median (IQR)
Number of cells at thawing, n 4 (4–4) 4 (4–4.8) 4 (4–5.5)
Number of embryos with ≥ 75% live cells at thawing, n (%) 15 (93.8%) 16 (100%) 15 (93.8%)
Number of embryos with 100% live cells at thawing, n (%) 10 (62.5) 10 (62.5) 11 (68.8%)
First cell division, h 9.8 (4.7–16.7) 8.1 (2.5–21.2) 11.8 (4.8–14.5)
Fourth cell division, h 33.4 (13.8–41.4) 30.6 (21.2–38.8) 22.5 (17.0–30.1)
Compaction, h 52.8 (45.0–60.3) 53.0 (41.0–63.4) 47.8 (40.6–55.3)
Cavitation, h 65.1 (53.3–70.8) 60.4 (50.1–72.6) 54.0 (43.6–63.5)a
Start of expansion, h 75.2 (69.8–90.4) 75.4 (65.4–86.6) 69.0 (66.0–75.9)
Number of blastocysts, n (%) 10 (62.5%) 10 (62.5%) 13 (81.3%)
High-quality embryo, n (%) 8 (50.0%) 5 (31.3%) 10 (62.5%)

IQR, interquartile range.

a

Number of embryos from start of culture.

b

p = 0.065 in comparison with control, Mann-Whitney U-test.