Table 1.
Embryo demographics at thawing, timing of different developmental stages after thawing, the number of embryos that developed into blastocysts, and the number of high-quality embryos following treatment with 0.25 or 0.5 μM fluoxetine.
| Embryo demographics and time difference from thawing (hours) | Control na = 16 median (IQR) | 0.25 μM fluoxetine na = 16 median (IQR) | 0.5 μM fluoxetine na = 16 median (IQR) |
|---|---|---|---|
| Number of cells at thawing, n | 4 (4–4) | 4 (4–4.8) | 4 (4–5.5) |
| Number of embryos with ≥ 75% live cells at thawing, n (%) | 15 (93.8%) | 16 (100%) | 15 (93.8%) |
| Number of embryos with 100% live cells at thawing, n (%) | 10 (62.5) | 10 (62.5) | 11 (68.8%) |
| First cell division, h | 9.8 (4.7–16.7) | 8.1 (2.5–21.2) | 11.8 (4.8–14.5) |
| Fourth cell division, h | 33.4 (13.8–41.4) | 30.6 (21.2–38.8) | 22.5 (17.0–30.1) |
| Compaction, h | 52.8 (45.0–60.3) | 53.0 (41.0–63.4) | 47.8 (40.6–55.3) |
| Cavitation, h | 65.1 (53.3–70.8) | 60.4 (50.1–72.6) | 54.0 (43.6–63.5)a |
| Start of expansion, h | 75.2 (69.8–90.4) | 75.4 (65.4–86.6) | 69.0 (66.0–75.9) |
| Number of blastocysts, n (%) | 10 (62.5%) | 10 (62.5%) | 13 (81.3%) |
| High-quality embryo, n (%) | 8 (50.0%) | 5 (31.3%) | 10 (62.5%) |
IQR, interquartile range.
a
Number of embryos from start of culture.
b
p = 0.065 in comparison with control, Mann-Whitney U-test.