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. 2016 Jun 16;8:144. doi: 10.3389/fnagi.2016.00144

Table 2.

Serious opioid interaction outcomes.

Opioids
+
Alcohol Sedatives Antihistamines Antipsychotics Muscle relaxants
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Additive/synergistic interaction
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Respiratory depression
Hypotension
Sedation
Coma
Death