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. 2016 Jun 16;8:139. doi: 10.3389/fnagi.2016.00139

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Copyright © 2016 Knight, McCann, Kauppinen and Coulthard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diffusion tensor MRI in Alzheimer's research. Panel (A) shows the directional information encoded by diffusion tensor imaging by color (red: left-right, green: anterior-posterior, blue: head-foot) and fractional anisotropy (high intensity implies high fractional anisotropy). Panel (B) shows how the directional information may be represented in a deterministic tractography analysis, and shows the regions consistently identified and changing in AD (Blue: Corpus callosum, red: uncinate fasciculus, green: superior lateral fasciculus).