TABLE I. Survival and Body Weights of Variously Treated Neonatal H Mice.
| Survival after 210 days | Body weights (g) | |||
|---|---|---|---|---|
| Treatment | Gender | 120 days | 210 days | |
| Sham | M | 22/27 (81.4%) | 31.4 ± 0.83 | 32.9 ± 1.24 |
| F | 20/25 (80.0%) | 27.8 ± 0.73 | 29.3 ± 0.84 | |
| MCS* | M | 24/30 (80.0%) | 27.3 ± 0.782 | 30.9 ± 0.78 |
| F | 18/25 (72.0%) | 23.5 ± 0.862 | 26.8 ± 1.11 | |
| MCS* + NAC (current smokers)** | M | 16/22 (72.7%) | 27.9 ± 0.692 | 30.7 ± 1.36 |
| F | 16/23 (69.6%) | 24.6 ± 0.832 | 27.8 ± 1.24 | |
| MCS* + Budesonide (current smokers)** | M | 32/43 (74.4%) | 25.6 ± 0.892 | 32.8 ± 0.72 |
| F | 36/44 (81.8%) | 21.8 ± 0.972 | 26.4 ± 0.751 | |
| MCS* + PEITC (current smokers)** | M | 16/21 (76.2%) | 26.1 ± 0.832 | 30.1 ± 1.54 |
| F | 22/29 (75.9%) | 23.1 ± 1.112 | 27.2 ± 1.38 | |
| MCS* + Budesonide (ex-smokers)*** | M | 24/31 (77.4%) | 26.4 ± 0.712 | 31.7 ± 0.80 |
| F | 37/45 (82.2%) | 22.1 ± 1.072 | 24.7 ± 0.791 | |
| MCS* + PEITC (ex-smokers)*** | M | 25/29 (86.2%) | 23.4 ± 0.703,4 | 31.0 ± 0.92 |
| F | 32/39 (82.1%) | 21.7 ± 0.703 | 24.9 ± 0931 | |
Body weight values are means ± SE within each experimental group.
*
Exposure to MCS started immediately after birth and continued for 120 days.
**
Treatment with chemopreventive agents started after weaning (30-35 days) and continued until the end of the experiment (210 days).
***
Treatment with chemopreventive agents started after discontinuing exposure to MCS (120 days) and continued until the end of the experiment (210 days).
1
p < 0.05,
2
p < 0.01, and
3
p < 0.001 as compared with the corresponding Sham;
4
p < 0.001, as compared with the corresponding MCS.