Table 1.

Candidate genes selection.

Candidate genes associated with HCV spontaneous clearance or response to therapy
Gene symbol	Chromosome location	Gene name	Number of SNPs in analysis
IL28B	19q13.13	Interleukin 28B (encoding IFN-gamma-3)	4
SOCS3	17q25.3	Suppressor of cytokine signaling 3	16
SOCS1	16p13.13	Suppressor of cytokine signaling 1	2
IL-10	1q31-q32	Interleukin 10	15
IL-18	11q22.2-q22.3	Interleukin 18	6
TNF-alpha	6p21.3	Tumor necrosis factor alpha	1
TGF-beta-1	19q13.1	Transforming growth factor, beta 1	4
IL-6	7p21	Interleukin 6	42
CTLA-4	2q33	Cytotoxic T-lymphocyte-associated protein 4	7
IFNG	12q14	Interferon, gamma	8
HLA genes:
HLA-DRB1	6p21.3	Major histocompatibility complex, class II, DR beta 1	5
HLA-DQB1	6p21.3	Major histocompatibility complex, class II, DQ beta 1	40