Table 4.
Association between lincRNA-p21 gene haplotypes with the risk of CAD or MI.
| Haplotypea | Controls | Cases | OR (95% CI) | P |
|---|---|---|---|---|
| Number (%) | Number (%) | |||
| CAD | n = 655 | n = 615 | ||
|
| ||||
| AAAG | 132.99 (10.2) | 124.70 (10.1) | 1.00 (0.77–1.30) | 0.994 |
| GAAG | 225.98 (17.3) | 171.45 (13.9) | 0.78 (0.63–0.97) | 0.023b |
| GAGA | 235.99 (18.0) | 242.27 (19.7) | 1.12 (0.92–1.37) | 0.266 |
| GAGG | 440.03 (33.6) | 421.58 (34.3) | 1.04 (0.88–1.22) | 0.685 |
| GGGA | 274.98 (21.0) | 267.15 (21.7) | 1.05 (0.87–1.27) | 0.633 |
|
| ||||
| MI | n = 655 | n = 279 | ||
|
| ||||
| AAAG | 132.99 (10.2) | 60.70 (10.9) | 1.09 (0.79–1.50) | 0.611 |
| GAAG | 225.98 (17.3) | 69.17 (12.4) | 0.68 (0.51–0.91) | 0.010b |
| GAGA | 235.99 (18.0) | 105.28 (18.9) | 1.07 (0.83–1.38) | 0.624 |
| GAGG | 440.03 (33.6) | 195.85 (35.1) | 1.08 (0.88–1.33) | 0.477 |
| GGGA | 274.98 (21.0) | 123.87 (22.2) | 1.08 (0.85–1.38) | 0.521 |
aThe allelic sequence in the haplotypes is in the following order: rs9380586, rs4713998, rs6930083, rs6931097. Haplotype with frequency less than 3% was pooled and not analyzed.
b P values under 0.05 were shown in bold font.