Table 2. The starting linear mixed (multi-level) model with IgG1 galactosylation as dependent variable is shown, as well as the final model after sequential removal of total IgE level, age, sex, CRP level, and schistosomiasis status as non-significant fixed effects.
Model | Effects | Parameter | b | P value | 95% CI | |
---|---|---|---|---|---|---|
Starting model | Fixed | Intercept | 47.64 | <0.001 | 43.44 | 51.84 |
Sex | 0.68 | 0.155 | −0.26 | 1.61 | ||
Age | −0.06 | 0.670 | −0.33 | 0.21 | ||
Log(CRP level) | −0.66 | 0.068 | −1.37 | 0.05 | ||
Log(Total IgE level) | −0.11 | 0.787 | −0.92 | 0.69 | ||
Schistosomiasis | −2.41 | 0.024 | −4.50 | −0.32 | ||
STH infection | −1.24 | 0.059 | −2.53 | 0.05 | ||
Random | Residual | 30.29 | <0.001 | 26.88 | 34.15 | |
Intercept (Community) | 5.55 | 0.052 | 2.02 | 15.21 | ||
Final model | Fixed | Intercept | 48.62 | <0.001 | 46.82 | 50.43 |
STH infection | −1.37 | 0.028 | −2.58 | −0.15 | ||
Random | Residual | 30.99 | <0.001 | 27.73 | 34.63 | |
Intercept (Community) | 8.47 | 0.019 | 3.68 | 19.51 |
The fixed-effect and random-effect/covariance estimates (b) for each parameter are given with the corresponding t-test P values and 95% confidence intervals. b indicates whether a relationship between the parameter and IgG1 galactosylation is positive or negative.