Table 2.
Studies assessing the effectiveness of nosocomial RSV infection prevention and control measures (research question two)
| Author, publication year | Country setting, study year | Hospital setting | Study objectivea | Study design |
|---|---|---|---|---|
| Agah, 198744 | USA, 1984–1985 | Paediatric | To assess RSV infection rates in staff exposed to RSV, comparing those who wore goggles and masks with those who did not | Experimental |
| Gala, 198645 | USA, 1984 | Neonatal/paediatric | To evaluate an eye–nose goggle in reducing nosocomial RSV infection in patients and staff | Experimental |
| Garcia, 199754 | USA, 1992–1994 | Adults – haematological cancers and/or bone marrow/stem cell transplant recipients | To assess the effectiveness of a multifaceted infection control strategy in limiting the nosocomial RSV infection among patients | Retrospective cohort |
| Gardner, 197355 | UK, 1970–1972 | Paediatric | To measure the extent and clinical importance of viral cross‐infection | Retrospective cohort |
| Hall, 198115 | USA, 1979 | Neonatal/paediatric | To evaluate the efficacy of use of gowns and masks on the rate of nosocomial RSV in infants and staff | Experimental |
| Hall, 197851 | USA, 1976 | Paediatric | To evaluate methods to control the spread of RSV infection on an infants ward during a community outbreak | Prospective cohort |
| Isaacs, 199116 | UK, 1986–1989 | Neonatal/paediatric | To investigate whether cohorting infants and handwashing will reduce the incidence of nosocomial RSV | Prospective and retrospective cohort |
| Karanfil, 199956 | USA, 1989–1997 | Paediatric | To report on implementation of control measures to prevent nosocomial RSV transmission | Retrospective cohort |
| Katz, 200957 | USA, 1990–2008 | Neonatal | To compare nosocomial RSV infection rate in a NICU before and after RSV prophylaxis | Retrospective cohort |
| Krasinski, 199046 | USA, 1987–1988 | Paediatric | To determine the efficacy of assignment to cohorts to reduce nosocomial RSV transmission | Prospective cohort |
| Langley, 199752 | Canada, 1992–1994 | Paediatric | To determine nosocomial RSV transmission, outcomes and infection control practices | Prospective cohort |
| Lavergne, 201158 | Canada, 1999–2003 | Adults – haematological cancers and/or bone marrow/stem cell transplant recipients | To evaluate impact of an enhanced infection control programme on incidence of nosocomial‐acquired RSV and its consequences | Retrospective cohort |
| Leclair, 198747 | USA, 1982‐1985 | Neonatal/paediatric | To investigate the efficacy of a vigorous infection control effort in reducing nosocomial RSV transmission | Prospective cohort |
| Macartney, 200048 | USA, 1988–1996 | Neonatal/paediatric | To determine the cost‐effectiveness and cost–benefit of an infection control programme to reduce nosocomial RSV transmission | Prospective cohort |
| Madge, 199218 | UK, 1989‐1992 | Neonatal/paediatric | To define the most effective infection control procedure for the prevention of nosocomial infection on wards with limited isolation facilities | Prospective cohort |
| Page, 200761 | USA, 1996–2002 | Paediatric | Reports on a comprehensive RSV isolation policy to prevent nosocomial RSV transmission | N/A (abstract only) |
| Raad, 199759 | USA, 1994–1996 | Adults – haematological cancers and/or bone marrow/stem cell transplant recipients | Reports on a multifaceted control strategy to reduce nosocomial RSV transmission | Retrospective cohort |
| Hall, 197753 | USA, NS | Neonatal/paediatric | To identify shedding patterns of RSV, spread of RSV infection within families (in a community setting) and nosocomial spread of RSV | Prospective cohort |
| Murphy, 198150 | USA, 1979 | Paediatric | To examine the effects of various control methods on the acquisition of symptomatic respiratory infections among medical staff caring for infants with respiratory disease | Prospective cohort |
| Simon, 200649 | Germany, 1999–2002 | Paediatric | To assess the local epidemiology of nosocomial RSV infections and evaluate the global efficacy of a complex intervention programme | Prospective cohort |
| Snydman, 198860 | USA, 1984–1986 | Neonatal | To investigate the impact of additional infection control methods for nosocomial RSV | Retrospective cohort |
RSV, respiratory syncytial virus; NICU, neonatal intensive care unit; PICU, paediatric intensive care unit; LRTI, lower respiratory tract infection; URTI, upper respiratory tract infection; NS, not specified.
a
Objectives explicitly stated by the study author begin with ‘To…’.