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Lung histopathology from swine inoculated with LPAI viruses. (A) Normal bronchiole and surrounding alveoli, sham control (score = 0). (B) Focal mild alveolitis, Mallard/H7N8 at 3 DPI (score = 2). (C) Mild bronchiolitis with moderate alveolitis, Emu/H5N9 at 5 DPI (3). (D) Moderate bronchiolitis with peribronchiolar edema and mononuclear inflammatory cells, and severe diffuse alveolitis with edema and interstitial mononuclear inflammatory cells, Swine/H1N1 at 5 DPI (score = 4).
