Table 4.

Alternative parameter settings

Sensitivity analysis scenario	Effect on vaccination effectiveness	Effect on QIV versus TIV relative effectiveness
Cross‐protection against non‐TIV B lineage	TIV more effective	TIV as effective as QIV if cross‐protection VE of at least 26%
Higher no‐vaccination attack rate	Larger absolute attack rate reduction; lower relative attack rate reduction	None
Lower vaccine efficacy	Vaccination less effective	None
Waning immunity	Vaccination less effective	None
Pre‐existing immunity lower in younger population	Transmitters‐first prioritisation more effective; vulnerable‐first prioritisation less effectives	None

QIV, quadrivalent influenza vaccine; TIV, trivalent inactivated vaccine.