Table 2.
Odds Of Malignancy In Univariate And Multivariate Analyses
| Univariate analysis (n = 536) | Multivariate analysis (n = 422) | |||
|---|---|---|---|---|
| Variable | OR (95%CI) | pa | OR (95%CI) | pa |
| TSH – upper tertile | 1.52 (1.19, 1.92) | 0.001 | 1.53 (1.10, 2.12) | 0.01 |
| FT4 - upper tertile | 0.82 (0.66, 1.02) | 0.08 | 0.84 (0.61, 1.15) | 0.28 |
| Age-group (<30 or > 60 yrs) | 1.16 (0.64, 2.09) | 0.62 | 1.17 (0.51, 2.71) | 0.71 |
| Male gender | 3.83 (2.04, 7.17) | <0.001 | 3.45 (1.33, 8.92) | 0.01 |
| Smoker | 0.93 (0.64, 1.38) | 0.75 | 1.02 (0.65, 1.60) | 0.93 |
| Size group | 0.79 (0.55, 1.15) | 0.23 | 0.78 (0.45, 1.37) | 0.40 |
| Microcalcification | 7.55 (4.07, 14.0) | <0.001 | 6.32 (2.82, 14.1) | <0.001 |
| Nodularity | 1.09 (0.59, 2.01) | 0.78 | 0.79 (0.36, 1.76) | 0.57 |
| Hypo-echogenicity | 1.52 (1.09, 2.10) | 0.01 | 1.17 (0.73, 1.89) | 0.51 |
| Irregular margins | 4.49 (1.76, 11.4) | 0.002 | 5.45 (1.61, 18.6) | 0.006 |
| Solid composition | 1.24 (0.82, 1.87) | 0.31 | 1.05 (0.62, 1.77) | 0.84 |
aCalculated using the Wald Test; Multivariate analysis is analysis adjusted for all variables shown in this table