Table 2.
Associations Between Prenatal Exposures and TTS Subscales [β (p-value)] by Linear Regression Modeling
| Activity | Rhythmicity | Approach | Adaptability | Intensity | Mood | Persistence | Distractibility | Threshold | |
|---|---|---|---|---|---|---|---|---|---|
| 1. SES | −0.014 (0.54) | −0.081 (0.005)* | −0.027 (0.47) | −0.017 (0.56) | −0.026 (0.28) | −0.040 (0.12) | 0.013 (0.55) | 0.034 (0.19) | 0.067 (0.030)* |
| 2. EPDS | 0.021 (0.0003)* | 0.029 (<0.0001)* | 0.020 (0.037)* | 0.031 (<0.0001)* | 0.005 (0.46) | 0.032 (<0.0001)* | 0.018 (0.001)* | 0.008 (0.24) | −0.020 (0.015)* |
| 3. Blood lead | −0.009 (0.38) | 0.016 (0.21) | −0.012 (0.46) | 0.018 (0.17) | −0.005 (0.63) | 0.005 (0.67) | 0.001 (0.91) | −0.002 (0.84) | −0.009 (0.53) |
| 4. Blood lead x EPDS | <0.001 (0.98) | −0.005 (0.11) | −0.004 (0.37) | −0.003 (0.46) | 0.006 (0.05)* | 0.001 (0.74) | 0.004 (0.11) | 0.004 (0.20) | 0.005 (0.14) |
| 5. Tibia lead | −0.002 (0.56) | 0.004 (0.32) | −0.001 (0.79) | −0.0008 (0.86) | −0.002 (0.67) | 0.0008 (0.84) | −0.003 (0.42) | −0.006 (0.11) | −0.011 (0.017)* |
| 6. Tibia lead x EPDS | <0.0001 (0.99) | −0.003 (0.01)* | −0.002 (0.22) | −0.001 (0.31) | −0.0003 (0.73) | −0.0008 (0.37) | 0.0007 (0.38) | −0.0009 (0.37) | −0.0001 (0.93) |
| 7. Mercury | 0.12 (0.49) | 0.28 (0.21) | −0.25 (0.40) | 0.16 (0.50) | 0.35 (0.07) | 0.10 (0.61) | −0.13 (0.45) | 0.30 (0.16) | 0.090 (0.71) |
| 8. Mercury x EPDS | 0.088 (0.04)* | 0.053 (0.33) | 0.002 (0.97) | 0.13 (0.03)* | 0.022 (0.64) | 0.071 (0.15) | 0.028 (0.51) | 0.031 (0.55) | 0.091 (0.13) |
Maternal blood lead and toenail mercury were measured in the second trimester of pregnancy. Tibia lead was measured by K-XRF one month post-partum
Models 2–8 were adjusted for SES
Models 4, 6, and 8 evaluated the interaction between exposures of interest
N = 500
*p ≤ 0.05