Table 2.
Statistical analysis of promiscuous peptides across every two supertypes
| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | T | U | V | W | X | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | -- | 193 | 152 | 81 | 131 | 28 | 98 | 22 | 207 | 295 | 32 | 24 | 319 | 61 | |||||||||
| B | 9 | -- | 119 | 68 | 114 | 71 | 100 | 45 | 115 | 156 | 31 | 23 | 29 | 37 | 1 | 1 | |||||||
| C | 3 | 4 | -- | 20 | 62 | 7 | 57 | 16 | 96 | 112 | 34 | 16 | 47 | 112 | 5 | 4 | 4 | 2 | 4 | ||||
| D | 5 | 16 | 3 | -- | 44 | 8 | 10 | 12 | 48 | 58 | 8 | 6 | 101 | 7 | |||||||||
| E | 3 | 15 | 3 | 11 | -- | 71 | 58 | 20 | 134 | 227 | 21 | 8 | 14 | 16 | |||||||||
| F | 3 | 1 | -- | 65 | 6 | 19 | 79 | 7 | 6 | 25 | 1 | 1 | 1 | 1 | |||||||||
| G | 3 | 1 | -- | 44 | 34 | 157 | 35 | 20 | 4 | 46 | |||||||||||||
| H | 1 | 2 | 1 | 1 | -- | 26 | 33 | 3 | 10 | 9 | 1 | ||||||||||||
| I | 1 | 1 | 2 | 2 | -- | 192 | 20 | 8 | 25 | 27 | |||||||||||||
| J | 1 | 2 | 3 | 3 | -- | 32 | 8 | 44 | 44 | 1 | 1 | ||||||||||||
| K | 3 | 2 | 2 | -- | 20 | 9 | 1 | ||||||||||||||||
| L | 4 | 5 | 1 | 1 | -- | 2 | 5 | ||||||||||||||||
| M | 10 | 1 | 2 | -- | 4 | ||||||||||||||||||
| N | 2 | 1 | 3 | 1 | 1 | -- | |||||||||||||||||
| O | 1 | 2 | -- | 192 | 99 | 200 | 310 | 168 | 270 | 285 | 265 | ||||||||||||
| P | 2 | -- | 104 | 336 | 341 | 177 | 292 | 320 | 292 | ||||||||||||||
| Q | 1 | 3 | -- | 138 | 127 | 92 | 134 | 108 | 100 | ||||||||||||||
| R | 1 | 1 | 43 | 4 | -- | 476 | 234 | 402 | 403 | 380 | |||||||||||||
| T | 19 | 2 | 10 | 5 | 1 | 9 | 17 | 26 | -- | 782 | 1714 | 1550 | 1310 | ||||||||||
| U | 9 | 4 | 1 | 6 | 7 | 1 | 9 | 53 | -- | 746 | 724 | 583 | |||||||||||
| V | 10 | 1 | 9 | 3 | 5 | 18 | 1 | 12 | 171 | 51 | -- | 1361 | 1088 | ||||||||||
| W | 6 | 1 | 1 | 7 | 8 | 13 | 93 | 38 | 71 | -- | 1089 | ||||||||||||
| X | 2 | 2 | 5 | 10 | 1 | 87 | 7 | 32 | 34 | -- |
Promiscuous peptides that can be presented by multiple HLA molecules within different supertypes were collected, and a statistical analysis of these promiscuous data across every two supertypes was performed. Statistics on promiscuous epitopes are shown in the lower triangle, and statistics on promiscuous binding peptides are shown in the upper triangle. The values in the table indicate the numbers of peptides that can be presented by HLA molecules within the two supertypes indicated in the row and column headers. The supertype names are presented in capital letters according to the labels in Table 1