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. 2016 Jun 16;35:93. doi: 10.1186/s13046-016-0371-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The overexpression of miR-155-3p enhances tumorigenesis in vitro. a Expression profile of miR-155-3p in Hepatocellular carcinoma cell lines. miR-155-3p RNA levels relative to normal liver cell line THLE-3 were determined by qRT-PCR. Gene expression was normalized to U6. Data are presented as means ± Standard deviation. b Establishment of BEL-7405-expressing miR-155-3p cells. The results were analyzed by qRT-PCR. c Proliferation of BEL-7405-miR-155-3p cells is significantly accelerated compared to normal BEL-7405 control cells measured by MTT assay. d Representative stained colonies are displayed. e The number of colonies was counted. **P < 0.01, unpaired two-tailed Student’s t-test